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Presynaptic establishment of the synaptic cleft extracellular matrix is required for post-synaptic differentiation

Formation and regulation of excitatory glutamatergic synapses is essential for shaping neural circuits throughout development. In a Drosophila genetic screen for synaptogenesis mutants, we identified mind the gap (mtg), which encodes a secreted, extracellular N-glycosaminoglycan-binding protein. MTG...

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Autors principals: Rohrbough, Jeffrey, Rushton, Emma, Woodruff, Elvin, Fergestad, Tim, Vigneswaran, Krishanthan, Broadie, Kendal
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000325/
https://ncbi.nlm.nih.gov/pubmed/17901219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1574107
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