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Kidney-specific enhancement of ANG II stimulates endogenous intrarenal angiotensinogen in gene-targeted mice

This study was performed in transgenic mice to test the hypothesis that the selective intrarenal overproduction of ANG II increases intrarenal mouse (m) angiotensinogen (AGT) expression. We used the following three groups: 1) single transgenic mice (group A, n = 14) expressing human (h) AGT only in...

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Autori principali: Kobori, Hiroyuki, Ozawa, Yuri, Satou, Ryousuke, Katsurada, Akemi, Miyata, Kayoko, Ohashi, Naro, Hase, Naoki, Suzaki, Yuki, Sigmund, Curt D., Navar, L. Gabriel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000297/
https://ncbi.nlm.nih.gov/pubmed/17634399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00146.2007
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