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Transmission of a fatal clonal tumor by biting occurs due to depleted MHC diversity in a threatened carnivorous marsupial

A fatal transmissible tumor spread between individuals by biting has emerged in the Tasmanian devil (Sarcophilus harrisii), a carnivorous marsupial. Here we provide genetic evidence establishing that the tumor is clonal and therefore foreign to host devils. Thus, the disease is highly unusual becaus...

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Detalhes bibliográficos
Main Authors: Siddle, Hannah V., Kreiss, Alexandre, Eldridge, Mark D. B., Noonan, Erin, Clarke, Candice J., Pyecroft, Stephen, Woods, Gregory M., Belov, Katherine
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1999395/
https://ncbi.nlm.nih.gov/pubmed/17911263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704580104
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