Degenerative knee joint lesions in mice after a single intra-articular collagenase injection. A new model of osteoarthritis.

A single intra-articular injection with bacterial collagenase in the right knee joints of 10-week-old male C57bl10 mice led to osteoarthritic lesions within a few weeks in these joints. The collagenase-induced osteoarthritis was characterized by severe degenerative cartilage lesions on the medial si...

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Bibliographic Details
Main Authors: van der Kraan, P. M., Vitters, E. L., van Beuningen, H. M., van de Putte, L. B., van den Berg, W. B.
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1998679/
https://ncbi.nlm.nih.gov/pubmed/2155638
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