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Daidzin inhibits mitochondrial aldehyde dehydrogenase and suppresses ethanol intake of Syrian golden hamsters

Daidzin is the major active principle in extracts of radix puerariae, a traditional Chinese medication that suppresses the ethanol intake of Syrian golden hamsters. It is the first isoflavone recognized to have this effect. Daidzin is also a potent and selective inhibitor of human mitochondrial alde...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Keung, Wing Ming, Klyosov, Anatole A., Vallee, Bert L.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19975/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9050837/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.5.1675
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