Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase)

A mammalian cytosolic FAD-dependent enzyme that catalyzes the reduction of quinones by N-ribosyl- and N-alkyldihydronicotinamides, but not by NADH, NADPH, or NMNH (reduced nicotinamide mononucleotide), was isolated from bovine kidney more than 30 years ago [S. Liao, J. T. Dulaney and H. G. Williams-...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Zhao, Qinjian, Yang, Xiao Ling, Holtzclaw, W. David, Talalay, Paul
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1997
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19974/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9050836/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.5.1669
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