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The yeast CLC chloride channel functions in cation homeostasis

A defect in the yeast GEF1 gene, a CLC chloride channel homolog leads to an iron requirement and cation sensitivity. The iron requirement is due to a failure to load Cu(2+) onto a component of the iron uptake system, Fet3. This process, which requires both Gef1 and the Menkes disease Cu(2+)-ATPase y...

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Detalhes bibliográficos
Main Authors: Gaxiola, Roberto A., Yuan, Daniel S., Klausner, Richard D., Fink, Gerald R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC19960/
https://ncbi.nlm.nih.gov/pubmed/9520490
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