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Calcimimetics with potent and selective activity on the parathyroid calcium receptor

Parathyroid hormone (PTH) secretion is regulated by a cell surface Ca(2+) receptor that detects small changes in the level of plasma Ca(2+). Because this G protein-coupled receptor conceivably provides a distinct molecular target for drugs useful in treating bone and mineral-related disorders, we so...

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Auteurs principaux: Nemeth, Edward F., Steffey, Michael E., Hammerland, Lance G., Hung, Benjamin C. P., Van Wagenen, Bradford C., DelMar, Eric G., Balandrin, Manuel F.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC19959/
https://ncbi.nlm.nih.gov/pubmed/9520489
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