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Nullomers: Really a Matter of Natural Selection?

BACKGROUND: Nullomers are short DNA sequences that are absent from the genomes of humans and other species. Assuming that nullomers are the signatures of natural selection against deleterious sequences in humans, the use of nullomers in drug target identification, pesticide development, environmenta...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Acquisti, Claudia, Poste, George, Curtiss, David, Kumar, Sudhir
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995752/
https://ncbi.nlm.nih.gov/pubmed/17925870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001022
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