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Physicochemical properties affecting lipofection potency of a new series of 1,2-dialkoylamidopropane-based cationic lipids

The in vitro transfection activity of a novel series of N,N(′)-diacyl-1,2-diaminopropyl-3-carbamoyl-(aminoethane) derivatives was evaluated against a mouse melanoma cell line at different +/- charge ratios, in the presence and absence of helper lipids. Only the unsaturated derivative N,N(′)-dioleoyl...

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Detalhes bibliográficos
Main Authors: Aljaberi, Ahmad, Spelios, Michael, Kearns, Molinda, Selvi, Bilge, Savva, Michalakis
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995744/
https://ncbi.nlm.nih.gov/pubmed/17336044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.colsurfb.2007.01.012
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