Regulatory functions of self-restricted MHC class II allopeptide-specific Th2 clones in vivo

We studied T-cell clones generated from grafts of rejecting and tolerant animals and investigated the regulatory function of Th2 clones in vitro and in vivo. To prevent allograft rejection, we treated LEW strain recipient rats of WF strain kidney grafts with CTLA4Ig to block CD28-B7 costimulation. W...

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Pubblicato in:	J Clin Invest
Autori principali:	Waaga, Ana Maria, Gasser, Martin, Kist-van Holthe, Joana E., Najafian, Nader, Müller, Angelika, Vella, John P., Womer, Karl L., Chandraker, Anil, Khoury, Samia J., Sayegh, Mohamed H.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 2001
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC199572/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11285310/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI11427
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