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Distinct ASIC currents are expressed in rat putative nociceptors and are modulated by nerve injury

The H(+)-gated acid-sensing ion channels (ASICs) are expressed in dorsal root ganglion (DRG) neurones. Studies with ASIC knockout mice indicated either a pro-nociceptive or a modulatory role of ASICs in pain sensation. We have investigated in freshly isolated rat DRG neurones whether neurones with d...

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Detalhes bibliográficos
Main Authors: Poirot, Olivier, Berta, Temugin, Decosterd, Isabelle, Kellenberger, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995627/
https://ncbi.nlm.nih.gov/pubmed/16840516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.113035
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