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Three amino acids that are critical to formation and stability of the P22 tailspike trimer

The P22 tailspike protein folds by forming a folding competent monomer species that forms a dimeric, then a non-native trimeric (protrimer) species by addition of folding competent monomers. We have found three residues, R549, R563, and D572, which play a critical role in both the stability of the n...

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Autores principales: Gage, Matthew J., Zak, Jennifer L., Robinson, Anne Skaja
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995594/
https://ncbi.nlm.nih.gov/pubmed/16081648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051394605
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