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Expression of IL-5 alters bone metabolism and induces ossification of the spleen in transgenic mice

We have developed a transgenic mouse line, NJ.1638, which expresses high levels of IL-5 from T cells, with profound hematological consequences. Eosinophils comprise more than 60% of circulating white blood cells in these animals, with the total peripheral white blood cell counts increasing more than...

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Hlavní autoři: Macias, MiMi P., Fitzpatrick, Lorraine A., Brenneise, Ina, McGarry, Michael P., Lee, James J., Lee, Nancy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC199553/
https://ncbi.nlm.nih.gov/pubmed/11306598
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