ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic K(ATP) channel gating

Stress tolerance of the heart requires high-fidelity metabolic sensing by ATP-sensitive potassium (K(ATP)) channels that adjust membrane potential-dependent functions to match cellular energetic demand. Scanning of genomic DNA from individuals with heart failure and rhythm disturbances due to idiopa...

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Bibliografische gegevens
Hoofdauteurs: Bienengraeber, Martin, Olson, Timothy M, Selivanov, Vitaliy A, Kathmann, Eva C, O’Cochlain, Fearghas, Gao, Fan, Karger, Amy B, Ballew, Jeffrey D, Hodgson, Denice M, Zingman, Leonid V, Pang, Yuan-Ping, Alekseev, Alexey E, Terzic, Andre
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2004
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995438/
https://ncbi.nlm.nih.gov/pubmed/15034580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1329
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