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Inhibitory costimulation and anti-tumor immunity
Costimulation was originally shown to be important in T-cell activation and effector differentiation. Recent characterization of B7/butyrophilin and members of the CD28 superfamily has revealed a large number of negative costimulatory molecules that dampen T-cell activation and regulate immune toler...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1995405/ https://ncbi.nlm.nih.gov/pubmed/17683946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2007.06.003 |
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