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Relationship Between Mitochondrial Electron Transport Chain Dysfunction, Development, and Life Extension in Caenorhabditis elegans

Prior studies have shown that disruption of mitochondrial electron transport chain (ETC) function in the nematode Caenorhabditis elegans can result in life extension. Counter to these findings, many mutations that disrupt ETC function in humans are known to be pathologically life-shortening. In this...

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書目詳細資料
Main Authors: Rea, Shane L, Ventura, Natascia, Johnson, Thomas E
格式: Artigo
語言:Inglês
出版: Public Library of Science 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994989/
https://ncbi.nlm.nih.gov/pubmed/17914900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050259
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