Relationship Between Mitochondrial Electron Transport Chain Dysfunction, Development, and Life Extension in Caenorhabditis elegans

Prior studies have shown that disruption of mitochondrial electron transport chain (ETC) function in the nematode Caenorhabditis elegans can result in life extension. Counter to these findings, many mutations that disrupt ETC function in humans are known to be pathologically life-shortening. In this...

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Autores principales: Rea, Shane L, Ventura, Natascia, Johnson, Thomas E
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994989/
https://ncbi.nlm.nih.gov/pubmed/17914900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050259
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