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Relationship Between Mitochondrial Electron Transport Chain Dysfunction, Development, and Life Extension in Caenorhabditis elegans

Prior studies have shown that disruption of mitochondrial electron transport chain (ETC) function in the nematode Caenorhabditis elegans can result in life extension. Counter to these findings, many mutations that disrupt ETC function in humans are known to be pathologically life-shortening. In this...

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Библиографические подробности
Главные авторы: Rea, Shane L, Ventura, Natascia, Johnson, Thomas E
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994989/
https://ncbi.nlm.nih.gov/pubmed/17914900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050259
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