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The Origins of Specificity in Polyketide Synthase Protein Interactions

Polyketides, a diverse group of heteropolymers with antibiotic and antitumor properties, are assembled in bacteria by multiprotein chains of modular polyketide synthase (PKS) proteins. Specific protein–protein interactions determine the order of proteins within a multiprotein chain, and thereby the...

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Bibliographic Details
Main Authors: Thattai, Mukund, Burak, Yoram, Shraiman, Boris I
Format: Artigo
Language:Inglês
Published: Public Library of Science 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994986/
https://ncbi.nlm.nih.gov/pubmed/17907798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030186
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