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High-level expression in Saccharomyces cerevisiae enables isolation and spectroscopic characterization of functional human adenosine A(2)a receptor
The G-protein coupled receptors (GPCRs) are a class of membrane proteins that trigger cellular responses to external stimuli, and are believed to be targets for nearly half of all pharmaceutical drugs on the market. However, little is known regarding their folding and cellular interactions, as well...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1994815/ https://ncbi.nlm.nih.gov/pubmed/17591446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2007.05.001 |
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