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Analysis of Protein Homology by Assessing the (Dis)similarity in Protein Loop Regions

Two proteins are considered to have a similar fold if sufficiently many of their secondary structure elements are positioned similarly in space and are connected in the same order. Such a common structural scaffold may arise due to either divergent or convergent evolution. The intervening unaligned...

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Detalhes bibliográficos
Main Authors: Panchenko, Anna R., Madej, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994810/
https://ncbi.nlm.nih.gov/pubmed/15382231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.20237
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