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staggerer phenotype in retinoid-related orphan receptor α-deficient mice

Retinoid-related orphan receptor α (RORα) is a member of the nuclear receptor superfamily. To study its physiological role we generated null-mutant mice by targeted insertion of a lacZ reporter gene encoding the enzyme β-galactosidase. In heterozygous RORα(+/−) mice we found β-galactosidase activity...

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Detalhes bibliográficos
Main Authors: Steinmayr, Markus, André, Elisabeth, Conquet, François, Rondi-Reig, Laure, Delhaye-Bouchaud, Nicole, Auclair, Nathalie, Daniel, Hervé, Crépel, Francis, Mariani, Jean, Sotelo, Constantino, Becker-André, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC19945/
https://ncbi.nlm.nih.gov/pubmed/9520475
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