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Thr164Ile polymorphism of β2‐adrenergic receptor negatively modulates cardiac contractility: implications for prognosis in patients with idiopathic dilated cardiomyopathy

BACKGROUND: β2‐adrenergic receptor Thr164Ile (threonine (Thr) is replaced by an isoleucine (Ile) at codon 164) polymorphism was postulated to contribute to lower exercise tolerance and poor prognosis in patients with congestive heart failure. However, heart failure is associated with several abnorma...

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Detalhes bibliográficos
Main Authors: Barbato, Emanuele, Penicka, Martin, Delrue, Leen, Van Durme, Frederic, De Bruyne, Bernard, Goethals, Marc, Wijns, William, Vanderheyden, Marc, Bartunek, Jozef
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994438/
https://ncbi.nlm.nih.gov/pubmed/17569809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/hrt.2006.091959
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