Expression of a cyclo‐oxygenase‐2 transgene in murine liver causes hepatitis

BACKGROUND: It has been proved that cyclo‐oxygenase‐2 (COX‐2) is rapidly induced by inflammatory mediators. However, it is not known whether overexpression of COX‐2 in the liver is sufficient to promote activation or secretion of inflammatory factors leading to hepatitis. AIM: To investigate the rol...

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Main Authors: Yu, Jun, Hui, Alex Y, Chu, Eagle S H, Cheng, Alfred S L, Go, Minnie Y Y, Chan, Henry L Y, Leung, Wai K, Cheung, Kin F, Ching, Arthur K K, Chui, Yiu L, Chan, Ka K, Sung, Joseph J Y
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Group 2007
Assuntos:
Liver Disease
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994375/
https://ncbi.nlm.nih.gov/pubmed/17148503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.097923
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