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Bonzo/CXCR6 expression defines type 1–polarized T-cell subsets with extralymphoid tissue homing potential

Chemokine receptor expression is finely controlled during T-cell development. We show that newly identified chemokine receptor Bonzo/CXCR6 is expressed by subsets of Th1 or T-cytotoxic 1 (Tc1) cells, but not by Th2 or Tc2 cells, establishing Bonzo as a differential marker of polarized type 1 T cells...

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Main Authors: Kim, Chang H., Kunkel, Eric J., Boisvert, Judie, Johnston, Brent, Campbell, James J., Genovese, Mark C., Greenberg, Harry B., Butcher, Eugene C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC199429/
https://ncbi.nlm.nih.gov/pubmed/11238560
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