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Increased sensitivity to dextran sodium sulfate colitis in IRE1β-deficient mice

The epithelial cells of the gastrointestinal tract are exposed to toxins and infectious agents that can adversely affect protein folding in the endoplasmic reticulum (ER) and cause ER stress. The IRE1 genes are implicated in sensing and responding to ER stress signals. We found that epithelial cells...

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Udgivet i:J Clin Invest
Principais autores: Bertolotti, Anne, Wang, XiaoZhong, Novoa, Isabel, Jungreis, Rivka, Schlessinger, Karni, Cho, Judy H., West, A. Brian, Ron, David
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2001
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC199427/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238559/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI11476
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