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Self-antigen–presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organs

Recent reports indicate that genes with tissue-restricted expression, including those encoding the type 1 diabetes autoantigens insulin, glutamic acid decarboxylase (GAD), and the tyrosine-phosphatase-like protein IA-2 (or ICA512), are transcribed in the thymus. The reported modulation of diabetes s...

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Detalhes bibliográficos
Main Authors: Pugliese, Alberto, Brown, Douglas, Garza, David, Murchison, Djanira, Zeller, Markus, Redondo, Maria, Diez, Juan, Eisenbarth, George S., Patel, Dhavalkumar D., Ricordi, Camillo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC199421/
https://ncbi.nlm.nih.gov/pubmed/11238556
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