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Cardiovascular risk reduction by reversing endothelial dysfunction:ARBs, ACE inhibitors, or both? Expectations from The ONTARGET Trial Programme

Endothelial dysfunction is the initial pathophysiological step in a progression of vascular damage that leads to overt cardiovascular and chronic kidney disease. Angiotensin II, the primary agent of the renin–angiotensin system (RAS), has a central role in endothelial dysfunction. Therefore, RAS blo...

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Detalhes bibliográficos
Main Authors: Ruilope, Luis Miguel, Redón, Josep, Schmieder, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994043/
https://ncbi.nlm.nih.gov/pubmed/17583170
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