Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis

Netrins are secreted molecules with roles in axonal growth and angiogenesis. The Netrin receptor UNC5B is required during embryonic development for vascular patterning, suggesting that it may also contribute to postnatal and pathological angiogenesis. Here we show that unc5b is down-regulated in qui...

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Главные авторы: Larrivée, Bruno, Freitas, Catarina, Trombe, Marc, Lv, Xiang, DeLafarge, Benjamin, Yuan, Li, Bouvrée, Karine, Bréant, Christiane, Del Toro, Raquel, Bréchot, Nicolas, Germain, Stéphane, Bono, Françoise, Dol, Frédérique, Claes, Filip, Fischer, Christian, Autiero, Monica, Thomas, Jean-Léon, Carmeliet, Peter, Tessier-Lavigne, Marc, Eichmann, Anne
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2007
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1993874/
https://ncbi.nlm.nih.gov/pubmed/17908930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.437807
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