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Oral delivery of low-molecular-weight heparin using sodium caprate as absorption enhancer reaches therapeutic levels

The primary objective of this study was to evaluate sodium caprate as an oral penetration enhancer for low molecular weight heparin (LMWH), ardeparin. In vitro studies using Caco-2 cell monolayer indicated that 0.0625% of sodium caprate gave approximately 2-fold enhancement of ardeparin compared to...

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Detalhes bibliográficos
Main Authors: MOTLEKAR, NUSRAT A., SRIVENUGOPAL, KALKUNTE S., WACHTEL, MITCHELL S., YOUAN, BI-BOTTI C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1993550/
https://ncbi.nlm.nih.gov/pubmed/16390818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10611860500471906
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