Rheumatoid arthritis synovial T cells regulate transcription of several genes associated with antigen-induced anergy

Rheumatoid arthritis (RA) is a chronic, inflammatory synovitis whose pathogenesis may involve autoimmune mechanisms. Anergy is a state of T-cell nonresponsiveness characterized by downregulated IL-2 production. Paradoxically, RA T cells are hyporesponsive and proliferate poorly to antigens and mitog...

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Bibliografiska uppgifter
Huvudupphovsmän: Ali, Manir, Ponchel, Frederique, Wilson, Katherine E., Francis, Michael J.D., Wu, Xia, Verhoef, Adrienne, Boylston, Arthur W., Veale, Douglas J., Emery, Paul, Markham, Alexander F., Lamb, Jonathan R., Isaacs, John D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2001
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC199240/
https://ncbi.nlm.nih.gov/pubmed/11181651
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