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Production, purification, crystallization and preliminary X-ray structural studies of adeno-associated virus serotype 5

Adeno-associated virus serotype 5 (AAV5) is under development for gene-therapy applications for the treatment of cystic fibrosis. To elucidate the structural features of AAV5 that control its enhanced transduction of the apical surface of airway epithelia compared with other AAV serotypes, X-ray cry...

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書誌詳細
主要な著者: DiMattia, Michael, Govindasamy, Lakshmanan, Levy, Hazel C., Gurda-Whitaker, Brittney, Kalina, Amy, Kohlbrenner, Erik, Chiorini, John A., McKenna, Robert, Muzyczka, Nicholas, Zolotukhin, Sergei, Agbandje-McKenna, Mavis
フォーマット: Artigo
言語:Inglês
出版事項: International Union of Crystallography 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1991325/
https://ncbi.nlm.nih.gov/pubmed/16511195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105028514
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