Production, purification, crystallization and preliminary X-ray structural studies of adeno-associated virus serotype 5

Adeno-associated virus serotype 5 (AAV5) is under development for gene-therapy applications for the treatment of cystic fibrosis. To elucidate the structural features of AAV5 that control its enhanced transduction of the apical surface of airway epithelia compared with other AAV serotypes, X-ray cry...

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מידע ביבליוגרפי
Main Authors: DiMattia, Michael, Govindasamy, Lakshmanan, Levy, Hazel C., Gurda-Whitaker, Brittney, Kalina, Amy, Kohlbrenner, Erik, Chiorini, John A., McKenna, Robert, Muzyczka, Nicholas, Zolotukhin, Sergei, Agbandje-McKenna, Mavis
פורמט: Artigo
שפה:Inglês
יצא לאור: International Union of Crystallography 2005
נושאים:
Crystallization Communications
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1991325/
https://ncbi.nlm.nih.gov/pubmed/16511195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105028514
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