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The sequence of the RNA primer and the DNA template influence the initiation of plus-strand DNA synthesis in hepatitis B virus

For hepadnaviruses the RNA primer for plus-strand DNA synthesis is generated by the final RNase H cleavage of the pgRNA at DR1 during the synthesis of minus-strand DNA. This RNA primer initiates synthesis at one of two distinct sites on the minus-strand DNA template resulting in two different end pr...

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Detalhes bibliográficos
Main Authors: Haines, Kathleen M., Loeb, Daniel D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1991300/
https://ncbi.nlm.nih.gov/pubmed/17531265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.04.057
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