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Data transferability from model organisms to human beings: Insights from the functional genomics of the flightless region of Drosophila

At what biological levels are data from single-celled organisms akin to a Rosetta stone for multicellular ones? To examine this question, we characterized a saturation-mutagenized 67-kb region of the Drosophila genome by gene deletions, transgenic rescues, phenotypic dissections, genomic and cDNA se...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Maleszka, R., de Couet, H. G., Miklos, George L. Gabor
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19905/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9520435/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.7.3731
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