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DIFFERENTIAL GENE EXPRESSION IN MOUSE LIVER ASSOCIATED WITH THE HEPATOPROTECTIVE EFFECT OF CLOFIBRATE

Pretreatment of mice with the peroxisome proliferator clofibrate (CFB) protects against acetaminophen (APAP)-induced hepatotoxicity. Previous studies have shown that activation of the nuclear peroxisome proliferator activated receptor α (PPARα) is required for this effect. The present study utilizes...

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Detalhes bibliográficos
Main Authors: Moffit, Jeffrey S, Koza-Taylor, Petra H, Holland, Ricky D, Thibodeau, Michael S, Beger, Richard D, Lawton, Michael P, Manautou, José E
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1989769/
https://ncbi.nlm.nih.gov/pubmed/17585979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2007.04.008
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