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Probability of the Site Juxtaposition Determines the Rate of Protein-Mediated DNA Looping

Numerous biological processes are regulated by DNA elements that communicate with their targets over a distance via formation of protein-bridged DNA loops. One of the first questions arising in studies of DNA looping is whether the rate of loop formation is limited by diffusion of the DNA sites. We...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Polikanov, Yury S., Bondarenko, Vladimir A., Tchernaenko, Vladimir, Jiang, Yong I., Lutter, Leonard C., Vologodskii, Alexander, Studitsky, Vasily M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1989718/
https://ncbi.nlm.nih.gov/pubmed/17573434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.111245
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