Probability of the Site Juxtaposition Determines the Rate of Protein-Mediated DNA Looping

Numerous biological processes are regulated by DNA elements that communicate with their targets over a distance via formation of protein-bridged DNA loops. One of the first questions arising in studies of DNA looping is whether the rate of loop formation is limited by diffusion of the DNA sites. We...

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Bibliografiske detaljer
Main Authors: Polikanov, Yury S., Bondarenko, Vladimir A., Tchernaenko, Vladimir, Jiang, Yong I., Lutter, Leonard C., Vologodskii, Alexander, Studitsky, Vasily M.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2007
Fag:
Nucleic Acids
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1989718/
https://ncbi.nlm.nih.gov/pubmed/17573434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.111245
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