The Mucosae-Associated Epithelial Chemokine (MEC/CCL28) Modulates Immunity in HIV Infection

BACKGROUND: CCL28 (MEC) binds to CCR3 and CCR10 and recruits IgA-secreting plasma cells (IgA-ASC) in the mucosal lamina propria (MLP). Mucosal HIV-specific IgA are detected in HIV-infection and exposure. The CCL28 circuit was analyzed in HIV-infected and-exposed individuals and in HIV-unexposed cont...

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Main Authors: Castelletti, Eleonora, Lo Caputo, Sergio, Kuhn, Louise, Borelli, Manuela, Gajardo, Johanna, Sinkala, Moses, Trabattoni, Daria, Kankasa, Chipepo, Lauri, Eleonora, Clivio, Alberto, Piacentini, Luca, Bray, Dorothy H., Aldrovandi, Grace M., Thea, Donald M., Veas, Francisco, Nebuloni, Manuela, Mazzotta, Francesco, Clerici, Mario
Format: Artigo
Language:Inglês
Published: Public Library of Science 2007
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1989139/
https://ncbi.nlm.nih.gov/pubmed/17912348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000969
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