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Sex Hormones Induce Direct Epithelial and Inflammation-Mediated Oxidative/Nitrosative Stress That Favors Prostatic Carcinogenesis in the Noble Rat
Oxidative and nitrosative stress have been implicated in prostate carcinogenesis, but the cause(s) of redox imbalance in the gland remains poorly defined. We and others have reported that administration of testosterone plus 17β-estradiol to Noble rats for 16 weeks induces dysplasia and stromal infla...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Investigative Pathology
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1988882/ https://ncbi.nlm.nih.gov/pubmed/17717140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070199 |
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