Refined Characterization of the Expression and Stability of the SMN Gene Products

Spinal muscular atrophy (SMA) is characterized by degeneration of lower motor neurons and caused by mutations of the SMN1 gene. SMN1 is duplicated in a homologous gene called SMN2, which remains present in patients. SMN has an essential role in RNA metabolism, but its role in SMA pathogenesis remain...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Vitte, Jérémie, Fassier, Coralie, Tiziano, Francesco D., Dalard, Cécile, Soave, Sabrina, Roblot, Natacha, Brahe, Christine, Saugier-Veber, Pascale, Bonnefont, Jean Paul, Melki, Judith
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2007
Sujets:
Regular Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1988876/
https://ncbi.nlm.nih.gov/pubmed/17717146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070399
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires