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Predominantly buried residues in the response regulator Spo0F influence specific sensor kinase recognition

Several alanine mutations in the response regulator Spo0F induce hypersporulation in Bacillus subtilis. L66A, I90A and H101A mutants are purported to be involved in contacts stabilizing the orientation of the α4-helix and hence the β4-α4 kinase recognition loop. Y13A is thought to affect the orienta...

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Detalhes bibliográficos
Main Authors: McLaughlin, Patrick D., Bobay, Benjamin G., Regel, Erin J., Thompson, Richele J., Hoch, James A., Cavanagh, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987376/
https://ncbi.nlm.nih.gov/pubmed/17350627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.02.061
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