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Role of homologous ASP334 and GLU319 in human non-gastric H,K- and Na,K-ATPases in cardiac glycoside binding

Cardiac steroids inhibit Na,K-ATPase and the related non-gastric H,K-ATPase, while they do not interact with gastric H,K-ATPase. Introducing an arginine, the residue present in the gastric H,K-ATPase, in the second extracellular loop at the corresponding position 334 in the human non-gastric H,K-ATP...

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Bibliografski detalji
Glavni autori: Radkov, Rossen, Kharoubi-Hess, Solange, Schaer, Danièle, Modyanov, Nikolai N., Geering, Käthi, Horisberger, Jean-Daniel
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987332/
https://ncbi.nlm.nih.gov/pubmed/17349614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.02.119
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