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Sequential Polymicrobial Infections Lead to CNS Inflammatory Disease: Possible Involvement of Bystander Activation in Heterologous Immunity

VV(PLP) is a recombinant vaccinia virus (VV) encoding myelin proteolipid protein (PLP) that has been used to investigate molecular mimicry and autoimmunity. Since virus infections can cause bystander activation, mice were first infected with VV(PLP), and later challenged with wild-type VV, lymphocyt...

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Autors principals: Tsunoda, Ikuo, Libbey, Jane E., Fujinami, Robert S.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987327/
https://ncbi.nlm.nih.gov/pubmed/17604850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.05.012
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