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Cardiovascular effects of bevantolol, a selective beta 1-adrenoceptor antagonist with a novel pharmacological profile.

Bevantolol was more potent in blocking the chronotropic than the hypotensive effects of isoprenaline in pithed rats. Bevantolol itself induced bradycardia, so that it was not possible to estimate the pA2 from nonparallel dose-response curves relating isoprenaline concentration to tachycardia. Bevant...

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Détails bibliographiques
Auteurs principaux: Dukes, I. D., Vaughan Williams, E. M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1985
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987306/
https://ncbi.nlm.nih.gov/pubmed/2858236
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