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Influence of age, sex, pregnancy and protein-calorie malnutrition on the pharmacokinetics of salicylate in rats.

The influence of age, sex, pregnancy and protein-calorie malnutrition (PCM) on the plasma t1/2, plasma clearance (Clp) and apparent volume of distribution (Vd) of sodium salicylate (62 mumol kg-1) was determined in Sprague-Dawley rats. Female and male rats of five different age groups (ages in weeks...

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Detalhes bibliográficos
Main Authors: Varma, D. R., Yue, T. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987258/
https://ncbi.nlm.nih.gov/pubmed/6428498
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