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Evidence that ethylenediamine acts in the isolated ileum of the guinea-pig by releasing endogenous GABA.

Ethylenediamine (EDA) released [3H]-gamma-aminobutyric acid ([3H]-GABA) in a dose-dependent manner from the isolated preloaded ileum of the guinea-pig maintained in Krebs-bicarbonate solution (pH 7.4, 37 degrees C), in the presence of beta-alanine and amino-oxyacetic acid (AOAA) to prevent GABA upta...

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Bibliographic Details
Main Authors: Kerr, D. I., Ong, J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1984
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987199/
https://ncbi.nlm.nih.gov/pubmed/6487887
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