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The role of accelerated colonic transit in prostaglandin-induced diarrhoea and its inhibition by prostacyclin.

Rats treated with subcutaneous 16,16-dimethyl prostaglandin E2 (16,16-dimethyl PGE2, 100 micrograms kg-1) exhibited diarrhoea even when their ileo-caecal junctions were tied, thereby eliminating contributions from small intestinal transit or fluid accumulation (enteropooling). The origin of the wate...

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Detalhes bibliográficos
Main Authors: Rush, B. D., Ruwart, M. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987172/
https://ncbi.nlm.nih.gov/pubmed/6386088
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