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Dual effect of (-)-N6-phenylisopropyl adenosine on guinea-pig trachea.

The effect of (-)-N6-phenylisopropyl adenosine (PIA), a metabolically stable P1-receptor agonist, was investigated on guinea-pig isolated trachea. PIA showed two opposite effects: contraction, evident at low concentrations (10(-7) to 2-5 X 10(-6) M), and relaxation at higher doses. Relaxation by PIA...

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Bibliographische Detailangaben
Hauptverfasser: Caparrotta, L., Cillo, F., Fassina, G., Gaion, R. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1984
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987161/
https://ncbi.nlm.nih.gov/pubmed/6435707
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