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Electrophysiological effects of alpha-adrenoceptor antagonists in rabbit sino-atrial node, cardiac Purkinje cells and papillary muscles.

The effects of prazosin, labetalol, and medroxalol were studied in the rabbit sino-atrial node, Purkinje cells and papillary muscles. At concentrations producing similar bradycardia, labetalol and medroxalol reduced the maximum rate of depolarization (Vmax) and overshoot potential in the sinus node....

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Detalles Bibliográficos
Main Authors: Dukes, I. D., Vaughan Williams, E. M.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1984
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987117/
https://ncbi.nlm.nih.gov/pubmed/6148983
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