Purinoceptor mediated stimulation of prostacyclin release in the porcine pulmonary vasculature.

Prostacyclin (PGI2) release from the piglet isolated perfused lung was measured by radioimmunoassay of 6-keto-PGF1 alpha in the venous effluent. Basal release of PGI2 was transiently stimulated up to 30 fold, in a dose-dependent manner, by bolus injections of ATP (0.03-3 mumol). A continuous infusio...

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Bibliografiska uppgifter
Huvudupphovsmän: Hellewell, P. G., Pearson, J. D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 1984
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987114/
https://ncbi.nlm.nih.gov/pubmed/6091831
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